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SMi is proud to announce the return the 12th annual Asthma & COPD conference 2016 in London!

Respiratory diseases represent an enormous and increasing healthcare and economic burden across Europe and USA.
Over the last few years, significant improvements in the management of asthma and COPD have been made, owing to new drugs, strategies and to the development of the nonpharmacologic treatment of COPD. Nevertheless, there are still many unmet needs in the treatment of these diseases. 

Join us at SMi's 12th annual Asthma & COPD taking place on the 11th - 12th April 2016 in London. This event will explore innovative asthma and COPD drug development programmes, directives and procedures which have been put in place to reduce the enormous suffering from lung disease and its high mortality.

 

 

A series of practical case studies, interactive roundtables and panel discussion facilitated by leading industry experts will provide executives with useful tools and best practices to:
• develop vaccination approaches for asthma
• improve inhaled therapies in COPD and development of antivirals
• evaluate the impact of COPD phenotypes on therapy
• explore biomarkers for respiratory drug assessment
• learn about stratified medicine and prevent exacerbation in asthma and COPD
 

and many more...

• Discuss the recent advances in asthma and COPD management
• Gain insight into the development of antivirals
• Evaluate the impact of COPD phenotypes on therapy
• Review the practice of personalized medicine
• Learn about stratified medicine
• Explore biomarkers for respiratory drug assessment
• Study the identification of new molecular targets
• Analyse developments of vaccination approaches for Asthma

   

Chief Executives, Chief Scientific Officers, Chief Medical Officers, Vice Presidents, Heads, Directors, Senior Scientist, Principle Scientists, Clinicians, Physicians, Project Leaders, Specialists, and Managers in the following areas:


• Respiratory Physiology & Medicine
• Respiratory Pharmacology
• Regulatory and Medical Affairs
• Inflammatory Disease
• Respiratory, Inflammation and Autoimmunity
• Pulmonary Disease
• Respiratory Therapeutics
• Immunology
• Medical & Inhalation Devices
• In-Vitro Biology
• Biomarker
• Inflammation Discovery
• Preclinical R&D
• Clinical Pharmacology
• Clinical Trials
• Research and Development
• Business Development
• Brand Manager
• Commercial
• Respiratory

3M Health Care; Aerocrine; Aerocrine AB; Amgen; Artimmune S.A.S; Asthma UK; Astrazeneca; AstraZeneca R&D Mölndal; AstraZeneca UK; Bayer Healthcare AG; Bayer Pharma AG; Biopharm Insight; Carclo Technical Plastics Ltd; Chiesi Farmaceutica SPA; Chiesi Group - Chiesi Farmaceutici S.p.A.; Fraunhofer Institut; Fraunhofer ITEM; Genentech, Inc.; Imperial College; Imperial College School of Medicine (N.H.L.I.); Imperial School Of Medicine London; Johnson and Johnson Pharmaceutical Services LLC; Liverpool School of Tropical Medicine; London North West Healthcare NHS Trust; Manchester University; MedImmune; Norwegian Hearth and Lung Patient Organisation; Osakidetza; Oxagen Ltd; Saba University ; SkyePharma AG; Synairgen Ltd; The University of Nottingham; Thermofisher Scientific; Thomson Reuters; University College London; University of Glasgow; University of Lyon; University Of Oxford; University of the Basque Country; Vectura; Verona Pharma; VIAJES ATLANTA, SA; VIVISOL; Zagreb Hospital Care ;

Conference programme

8:30 Registration & Coffee

9:00 Chairman's Opening Remarks

Ewan Walters

Ewan Walters, Medical Director, Teva UK Ltd

9:10 Recent advances in asthma and COPD management

Neil C Thomson

Neil C Thomson, Professor of Respiratory Medicine, University of Glasgow

  • Management of chronic asthma including severe disease
  • Pharmacological treatments for COPD
  • Management of the asthma-COPD overlap syndrome
  • Assessment of potential impact of drugs under development for asthma and COPD
  • 9:50 COPD: Unmet need and challenges in NHS care

    John Hurst

    John Hurst, Senior Clinical Lecturer, Honorary Consultant, University College London

     

  • Exploring the care needs of patients
  • The challenge of patients' unmet palliative care
  • Ten key challenges, representing unmet need, in NHS Care for COPD
  • 10:30 Morning Coffee

    11:00 Developing and registering new inhalers to deliver clinical benefits in asthma

    Ewan Walters

    Ewan Walters, Medical Director, Teva UK Ltd

  • Approval process for inhalers in asthma
  • Developing a new inhaler – delivering incremental improvements 
  • Real world data to assess performance for patients and HCPs of new inhalers
  • Characteristics of a new inhaler to provide benefit 
  • Assessment of training procedures in both HCP (doctors and nurses) and patients 
  • Clinical studies in real world and role of observational studies in clinical practice 
  • 11:40 Development challenges for Generic Inhalation Products for EU and US markets

    Nayna  Govind

    Nayna Govind, Director for the development of generic inhalation products , Dr Reddys Laboratories

  • Formulation and device considerations
  • In-vitro bioequivalence
  • EU & US regulatory requirements

     

  • 12:20 Networking Lunch

    13:30 Formulation and process challenges in the development of inhaled products

    Frank Thielmann

    Frank Thielmann, Operational Lead, Inhalation New Solids, Novartis Pharma AG

  • Device and formulation systems and their selection
  • Properties of drug substance and product and impact on in-vitro/ vivo performance
  • Challenges in the manufacturing of DPI systems
  • Future trends in inhaled drug delivery
  • 14:10 RPL554, a novel "first-in-class" inhaled drug for the treatment of exacerbations of chronic obstructive pulmonary disease (COPD), and cystic fibrosis

    Jan-Anders Karlsson

    Jan-Anders Karlsson, CEO , Verona Pharma

  • Treatment and prevention of COPD exacerbations
  • Severe exacerbations of COPD and hospital re-admissions shortly after discharge
  • RPL554 – a novel dual PDE3 and PDE4 inhibitor with bronchodilator and anti-inflammatory effect
  • 14:50 Afternoon Tea

    15:20 PANEL DISCUSSION: Are children over-diagnosed and trivialised?

    16:00 Chairman’s Closing Remarks and Close of Day One

    Ewan Walters

    Ewan Walters, Medical Director, Teva UK Ltd

    8:30 Registration & Coffee

    9:00 Chairman's Opening Remarks

    Peter Daley Yates

    Peter Daley Yates, Director Clinical Pharmacology, GSK

    9:10 Design implications and challenges in developing treatments for idiopathic pulmonary fibrosis

    Andy Kenwright

    Andy Kenwright, Project Statistician , Roche Products Limited

  •  Background to current state of play in treating IPF
  • Clinical development challenges in IPF
  • Combination therapy – is it the future ?
  • 9:50 A pivotal role for the alarmin IL-33 during respiratory exacerbations

    Matthew  Robinson

    Matthew Robinson, Senior Scientist, MedImmune

  • The alarmin IL-33 is increased in the lungs of COPD patients
  • IL-33 exacerbates lung inflammation in a mouse model of smoke and virus challenge
  • IL-33 function is attenuated over time by oxidation
  • 10:30 Morning Coffee

    11:00 Clinical development of "generic" DPls

    Katerina Athanassiou

    Katerina Athanassiou, CR Director, ELPEN Pharmaceutical Co. Inc

  • EMA regulations about the clinical development of OIP
  • Regulatory obstacles on the development
  •  Is the term “generic” applicable to DPIs?
  • 11:40 Scientific aspects of quality regulations in respiratory drug development

    Stefan Leiner

    Stefan Leiner, Chemical-Pharmaceutical Expert, Boehringer Ingelheim

  • What are the current philosophical differences between US and EU quality regulations for inhalation products?
  • How do they translate into current hot topics, e.g. generic approval
  • What would be quality requirements for future therapies (lung cancer, sustained release)?
  • 12:20 Networking Lunch

    13:30 Improving inhealed therapies

    Peter Daley Yates

    Peter Daley Yates, Director Clinical Pharmacology, GSK

  • Improving adherence
  • Improving drug delivery by inhaler and formulation performance
  • Improving pharmacology with new molecules and combination
  • 14:10 Performance Characterisation of Inhalation Products

    Jan Olof Svensson

    Jan Olof Svensson, Principle Scientist AstraZeneca R&D, AstraZeneca

  • Performance characterization in general
  • In-vivo relevant testing
  • Different types of delivery systems - different challenges
  • 14:50 Afternoon Tea

    15:20 Comparison of generic OIP experiences in different markets

    Michelle Lee-Bourner

    Michelle Lee-Bourner, Head of Regulatory, Mylan Pharma UK

  • An overview of the regulatory requirements for key markets globally
  • Market preferences and payer pressures
  • The key scientific challenges in the key markets.
  • Is one global development program ever likely to be possible?
  • 16:00 Corticosteroid insensitivity in severe asthma: Mechanisms and new targets

    Pankaj Bhavsar

    Pankaj Bhavsar, Research Lecturer, Imperial College London

  • Relative corticosteroid  (CS) insensitivity is displayed in both inflammatory and structural cells of patients with severe asthma compared to non-severe asthma
  • Decreased glucocorticoid receptor (GR) expression with impaired nuclear translocation in airway smooth muscle cells (ASMC), associated with reduced dexamethasone-mediated attenuation of p65 recruitment to gene promoters, may underlie the mechanism of CS insensitivity in severe asthma
  • Therapies to overcome corticoid insensitivity could be targeted at improving nuclear translocation of GR in ASMC of severe asthma patients; p38 MAPK inhibitors also provide a potential new therapy for the treatment.
  • 16:40 Chairman’s Closing Remarks and Close of Day Two

    Peter Daley Yates

    Peter Daley Yates, Director Clinical Pharmacology, GSK

    +

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    97 Cromwell Road , London, United Kingdom

    Holiday Inn Kensington Forum is perfectly situated in one of London’s most luxurious and beautiful areas within South Kensington. 

    The hotel is just 2 minutes walk from Gloucester Road tube station for convenient travel to Hyde Park, London Eye, Tower Bridge plus more of London’s top attractions. There are also easy and direct links to some major transport hubs including Victoria, Kings Cross St Pancras, Paddington and Heathrow. 

    This distinctive hotel in south London has so much to offer to make all guests really feel at home. The latest Holiday Inn relaunch is not just about the new look and feel for the hotel but to offer guests more benefits during their stay including a pillow menu for extra comfort during their sleep and a curved shower rail for more spacious feel. 

    In addition to our 906 rooms, all business guests can take advantage of our meeting and conference facilities including High Speed Internet Access and unlimited Starbucks coffee at The Academy. Our hotel’s professional event planners are on board to help take the hard work and stress away from planning your next event. 

    So whether you in London on business or pleasure, make the Holiday Inn London Kensington Forum your first choice of hotel and book your accommodation for our lowest internet rate guarantee. 

    HOTEL BOOKING FORM

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    Fidelta

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    Fidelta is highly qualified to conduct and support projects in discovery and early pre-clinical development. We offer a complete integrated drug discovery capability of medicinal chemistry, pharmacology and ADME/PK and have extensive experience in taking projects through the Hit to Lead and Lead Optimisation phases. With a strong emphasis on translational science we focus on patient derived and disease-relevant test models/systems. Our pharmacology portfolio includes design and execution of in vitro studies on human primary cells and disease tissue samples as well as ex vivo analyses for biomarker selection. Comprenhensive animal models of asthma, COPD and pulmonary fibrosis complement our extensive expertise in the respiratory area. Entrust us with your research project to gain high quality results.

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    Contract-Biotechnology.com is a web-based platform for laboratory outsourcing solutions. We are an online R&D matching tool that connects Scientifics and organizations involved in discovery, development and delivery of new healthcare products with service and products providers worldwide. Life science information technology is undergoing a revolution. Part of that revolution involves new, unexplored business models, open innovation, open data and collaboration. If you have a project or idea that you would like to propose, develop or run, we can help. A New Collaboration Network Model for Discovery Research and Development • Effective Platform: the 95% • 5.000 registered users // > 15.000 Newsletter subscribers • Geographical background: 45,5% Europe / 37,5% North America / 16,5% Asia / 0,5% ROW • Professional background: Outsourcing Manager, Project Manager, CEO, Business Developer, CSO, Account Manager, Sales & Marketing People, Scientists, R&D. For further information, please visit our website www.contract-biotechnology.com


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    COPD: Journal of Chronic Obstructive Pulmonary Disease publishes advances in the pathophysiology, diagnosis, management, and control of lung and airway disease and inflammation - providing a unique forum for the discussion, design, and evaluation of more efficient and effective strategies in patient care.


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    For over a decade DDW has continued to be the ‘must read’ journal within the DD&D Arena. DDW is recognised for voicing the opinions of some of the Industry’s leading luminaries and has become a recognised platform for Industry Gurus to debate some of the more challenging technological and business issues facing the the life science industry. DDW adheres to the maxim..... ‘Turning Science into Business’ DDW examines the advances in new technologies and the associated implications within the context of developing new and efficacious therapeutics. DDW is distinguishable in that it reaches out to a global audience at both bench and boardroom level, allowing both camps to profit from the uncomplicated style of editorial but at the same time challenges our readers to look at new ways to overcome discovery bottlenecks, embrace nascent technologies and build next generation technology platforms.


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    Pharmaceutical Manufacturing and Packing Sourcer (PMPS) is a specialist journal designed to provide worldwide coverage of a range of topics relating to the pharmaceutical supply chain sector.

    Published quarterly, the journal functions as a platform of communication and information-sharing for executive and strategic decision-makers within the industry, identifying new trends and marketing opportunities as well as highlighting the latest innovations in this dynamic environment. PMPS is specifically designed to interest those in the pharmaceutical drug delivery, manufacturing, logistics, packaging and product formulation industries who are actively seeking to source services for improved efficiency in what is an increasingly competitive market.

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    Biocompare.com is the leading resource for up-to-date product information, product reviews, and new technologies for life scientists. Biocompare combines an in-depth knowledge of life science products and new technologies with the power of the Internet to offer scientists the most dynamic, relevant, and innovative media-based marketplace for life science information.


    Gate2Biotech

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    Gate2Biotech is a portal that unites biotechnological community in Central Europe. It covers all the news in the field of biotechnology. Thanks to the the portal the companies engaged in the field can easily search for research institutions and other partners to solve technical problems they are facing and here they can also present their services offer to potential partners from the Czech Republic and abroad. Gate2Biotech portal serves as a bridge connecting scientific and commercial sector. It incorporates offices and support organizations dedicated to promoting transfer of innovative technologies into a unified communication platform of Czech and international biotechnologies. As a mediator of information it draws attention to biotechnologies and support of their application and transfer into practice. It also functions as a tool for encouraging non-professionals (especially scientists and students) towards innovative business or applied research.


    Swiss Biotech Association

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    Holiday Inn Kensington Forum

    97 Cromwell Road
    London SW7 4DN
    United Kingdom

    Holiday Inn Kensington Forum

    Holiday Inn Kensington Forum is perfectly situated in one of London’s most luxurious and beautiful areas within South Kensington. 

    The hotel is just 2 minutes walk from Gloucester Road tube station for convenient travel to Hyde Park, London Eye, Tower Bridge plus more of London’s top attractions. There are also easy and direct links to some major transport hubs including Victoria, Kings Cross St Pancras, Paddington and Heathrow. 

    This distinctive hotel in south London has so much to offer to make all guests really feel at home. The latest Holiday Inn relaunch is not just about the new look and feel for the hotel but to offer guests more benefits during their stay including a pillow menu for extra comfort during their sleep and a curved shower rail for more spacious feel. 

    In addition to our 906 rooms, all business guests can take advantage of our meeting and conference facilities including High Speed Internet Access and unlimited Starbucks coffee at The Academy. Our hotel’s professional event planners are on board to help take the hard work and stress away from planning your next event. 

    So whether you in London on business or pleasure, make the Holiday Inn London Kensington Forum your first choice of hotel and book your accommodation for our lowest internet rate guarantee. 

    HOTEL BOOKING FORM

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    WHAT IS CPD?

    CPD stands for Continuing Professional Development’. It is essentially a philosophy, which maintains that in order to be effective, learning should be organised and structured. The most common definition is:

    ‘A commitment to structured skills and knowledge enhancement for Personal or Professional competence’

    CPD is a common requirement of individual membership with professional bodies and Institutes. Increasingly, employers also expect their staff to undertake regular CPD activities.

    Undertaken over a period of time, CPD ensures that educational qualifications do not become obsolete, and allows for best practice and professional standards to be upheld.

    CPD can be undertaken through a variety of learning activities including instructor led training courses, seminars and conferences, e:learning modules or structured reading.

    CPD AND PROFESSIONAL INSTITUTES

    There are approximately 470 institutes in the UK across all industry sectors, with a collective membership of circa 4 million professionals, and they all expect their members to undertake CPD.

    For some institutes undertaking CPD is mandatory e.g. accountancy and law, and linked to a licence to practice, for others it’s obligatory. By ensuring that their members undertake CPD, the professional bodies seek to ensure that professional standards, legislative awareness and ethical practices are maintained.

    CPD Schemes often run over the period of a year and the institutes generally provide online tools for their members to record and reflect on their CPD activities.

    TYPICAL CPD SCHEMES AND RECORDING OF CPD (CPD points and hours)

    Professional bodies and Institutes CPD schemes are either structured as ‘Input’ or ‘Output’ based.

    ‘Input’ based schemes list a precise number of CPD hours that individuals must achieve within a given time period. These schemes can also use different ‘currencies’ such as points, merits, units or credits, where an individual must accumulate the number required. These currencies are usually based on time i.e. 1 CPD point = 1 hour of learning.

    ‘Output’ based schemes are learner centred. They require individuals to set learning goals that align to professional competencies, or personal development objectives. These schemes also list different ways to achieve the learning goals e.g. training courses, seminars or e:learning, which enables an individual to complete their CPD through their preferred mode of learning.

    The majority of Input and Output based schemes actively encourage individuals to seek appropriate CPD activities independently.

    As a formal provider of CPD certified activities, SMI Group can provide an indication of the learning benefit gained and the typical completion. However, it is ultimately the responsibility of the delegate to evaluate their learning, and record it correctly in line with their professional body’s or employers requirements.

    GLOBAL CPD

    Increasingly, international and emerging markets are ‘professionalising’ their workforces and looking to the UK to benchmark educational standards. The undertaking of CPD is now increasingly expected of any individual employed within today’s global marketplace.

    CPD Certificates

    We can provide a certificate for all our accredited events. To request a CPD certificate for a conference , workshop, master classes you have attended please email events@smi-online.co.uk

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    Contact SMi GROUP LTD

    UK Office
    Opening Hours: 9.00 - 17.30 (local time)
    SMi Group Ltd, 1 Westminster Bridge Road, London, SE1 7XW, United Kingdom
    Tel: +44 (0) 20 7827 6000 Fax: +44 (0) 20 7827 6001
    Website: http://www.smi-online.co.uk Email: events@smi-online.co.uk
    Registered in England No: 3779287 VAT No: GB 976 2951 71




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